Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CCR1 | P32246 | 2/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SORD | Q00796 | 1/20 | 0.30 |
| ▸ | FASN | P49327 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL882969 | 0.78 | SORD (0.45) | ALOX15KMT2ANPSR1RAB9ANPC1 | |
| SCHEMBL29206309 | 0.77 | LMNA (0.45) | LMNAKMT2APAX8RAB9ANPC1 | |
| SCHEMBL23193258 | 0.77 | ALOX15 (0.36) | ALOX15KMT2AUHRF1NPSR1RAB9A | |
| SCHEMBL17819845 | 0.75 | ALOX15 (0.36) | ALOX15KMT2ANPSR1RAB9ANPC1 | |
| SCHEMBL1578222 | 0.74 | KMO (0.51) | ALOX15KMT2AKMO | |
| SCHEMBL23193294 | 0.74 | LMNA (0.50) | LMNAKMT2APAX8NPSR1RAB9A | |
| SCHEMBL23370255 | 0.74 | SYK (0.35) | LMNAKMT2APAX8RAB9ANPC1 | |
| SCHEMBL2465653 | 0.72 | KMT2A (0.50) | ALOX15KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22072451 | 0.72 | KMT2A (0.42) | ALOX15KMT2AUHRF1L3MBTL1MAPT | |
| SCHEMBL28559148 | 0.72 | ALOX15 (0.36) | ALOX15KMT2AUHRF1NPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021159015-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-08-12 | — | — | WO | disclosed |