Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.36 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1124874 | 0.75 | NR1H2 (0.55) | NR1H2NR1H3 | |
| SCHEMBL9169732 | 0.75 | ESR1 (0.47) | ESR1TACR1FABP4FABP5CCNC | |
| SCHEMBL9162858 | 0.70 | ABCG2 (0.43) | ESR1TACR1DHODH | |
| SCHEMBL4712613 | 0.70 | CSNK1D (0.44) | NR1H2CSNK1DKCNJ5KCNJ3P2RX7 | |
| SCHEMBL28328975 | 0.69 | GRM5 (0.46) | ESR1 | |
| SCHEMBL29712652 | 0.69 | GRM5 (0.46) | ESR1 | |
| SCHEMBL11814128 | 0.67 | GRIN2B (0.46) | CSNK1DKCNJ5KCNJ3GRIN2B | |
| SCHEMBL8784587 | 0.67 | ALDH1A1 (0.49) | ESR1FABP4FABP5 | |
| SCHEMBL439770 | 0.66 | BACE1 (0.42) | CSNK1DCCNCCDK8NPBWR1 | |
| SCHEMBL10436780 | 0.65 | PIK3CA (0.57) | CCNCCDK8DHODHNPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368514-B1 | TRISUBSTITUTED SILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2021-08-18 | — | — | EP | claimed |