Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438632 | 0.87 | PARP1 (0.45) | BACE1NPBWR1NOS3NOS2ALDH1A1 | |
| SCHEMBL23935164 | 0.83 | BACE1 (0.45) | BACE1NPBWR1EPHX2SCN4ANOS3 | |
| SCHEMBL29742208 | 0.83 | BACE1 (0.45) | BACE1NPBWR1EPHX2SCN4ANOS3 | |
| SCHEMBL436530 | 0.81 | BACE1 (0.42) | BACE1NPBWR1EPHX2SCN4ANOS3 | |
| SCHEMBL439645 | 0.78 | ACHE (0.46) | BACE1CYP1A2MAP4K4AXL | |
| SCHEMBL439464 | 0.78 | NR4A2 (0.55) | EGFRCYP1A2MAP4K4CYP2D6 | |
| SCHEMBL437175 | 0.77 | NPC1 (0.44) | SCN4ASMN1; SMN2CYP1A2CYP3A4CDK2 | |
| SCHEMBL439948 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4ECYP1A2CHEK1AURKA | |
| SCHEMBL18658922 | 0.75 | ALDH1A1 (0.47) | BACE1ALDH1A1KDM4EPOLBCYP3A4 | |
| SCHEMBL30050271 | 0.75 | CCNC (0.48) | BACE1NOS3NOS2KDM4EEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |