SCHEMBL23748342

SCHEMBL23748342

Cc1ncc(CI)c(N)n1

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.61
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 2/20 0.45
CYP1A2 P05177 1/20 0.45
TSHR P16473 1/20 0.45
TKT P29401 5/20 0.44
HSP90AA1 P07900 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL30565607 0.98 LMNA (0.59) LMNAKDM4EALDH1A1CYP1A2TSHR
SCHEMBL12346332 0.81 LMNA (0.63) LMNAKDM4EALDH1A1CYP1A2TSHR
SCHEMBL478879 0.81 LMNA (0.63) LMNAKDM4EALDH1A1CYP1A2TSHR
SCHEMBL23748348 0.81 LMNA (0.63) LMNAKDM4EALDH1A1CYP1A2TSHR
SCHEMBL29895545 0.81 LMNA (0.63) LMNAKDM4EALDH1A1CYP1A2TSHR
SCHEMBL16015176 0.79 LMNA (0.61) LMNAKDM4EALDH1A1CYP1A2TSHR
Hydrochloric Acid SCHEMBL479404 0.79 LMNA (0.61) LMNAKDM4EALDH1A1CYP1A2TSHR
SCHEMBL23973989 0.79 LMNA (0.61) LMNAKDM4EALDH1A1CYP1A2TSHR
SCHEMBL4358570 0.79 LMNA (0.61) LMNAKDM4EALDH1A1CYP1A2TSHR
SCHEMBL20310245 0.79 LMNA (0.61) LMNAKDM4EALDH1A1CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11969002-B2 Savoury and mouthfulness taste enhancers LUCTA, S.A. (ES) 2024-04-30 US disclosed
EP-3864012-B1 SAVOURY AND MOUTHFULNESS TASTE ENHANCERS LUCTA S A (ES) 2023-09-13 EP disclosed
US-20210337850-A1 SAVOURY AND MOUTHFULNESS TASTE ENHANCERS LUCTA, S.A. (ES) 2021-11-04 US disclosed
EP-3864012-A1 SAVOURY AND MOUTHFULNESS TASTE ENHANCERS Lucta, S.A. (ES) 2021-08-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210337850-A1 SAVOURY AND MOUTHFULNESS TASTE ENHANCERS KCNJ6, TAS1R1, TAS2R5 LMNA 3556/4885KDM4E 699/4885ALDH1A1 1833/4885
US-11969002-B2 Savoury and mouthfulness taste enhancers TAS1R1, KCNJ6, KCNJ5 LMNA 3413/4885KDM4E 815/4885ALDH1A1 1527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.