SCHEMBL23748537

SCHEMBL23748537

CC1(C)O[Si](C)(c2ccccc2)CCC1(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.32
OPRK1 P41145 1/20 0.32
OPRL1 P41146 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7857746 0.81
SCHEMBL9751915 0.79 OPRM1 (0.32) OPRM1OPRK1OPRL1CYP2D6
SCHEMBL8018743 0.77 OPRL1 (0.33) OPRM1OPRK1OPRL1MEN1KMT2A
SCHEMBL9463971 0.75 OPRM1 (0.30) OPRM1OPRK1OPRL1
SCHEMBL8405436 0.74 HSD11B1 (0.34) OPRM1OPRK1OPRL1CYP2D6
SCHEMBL2369730 0.73 OPRM1 (0.31) OPRM1OPRK1OPRL1MEN1KMT2A
SCHEMBL3263249 0.71
SCHEMBL2048189 0.70 OPRM1 (0.33) OPRM1OPRK1OPRL1MEN1KMT2A
SCHEMBL10711079 0.69 MEN1 (0.35) OPRM1OPRK1OPRL1MEN1KMT2A
SCHEMBL28238211 0.69 CHRNB2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3863593-A1 PROCESS FOR TREATING KERATIN FIBERS EMPLOYING AN ANHYDRIDE ACRYLIC POLYMER IN OILY DISPERSION AND AN AMINE COMPOUND L'OREAL (FR) 2021-08-18 EP disclosed