Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4367842 | 0.83 | PDE1C (0.34) | NPC1RAB9AMEN1KMT2ATLR4 | |
| SCHEMBL4649386 | 0.79 | CA2 (0.37) | NPC1RAB9AMEN1KMT2ATLR4 | |
| SCHEMBL9281870 | 0.78 | — | — | |
| SCHEMBL6710688 | 0.75 | TSHR (0.32) | MEN1KMT2AMAOAMAOB | |
| SCHEMBL4757678 | 0.75 | KMT2A (0.35) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL5289688 | 0.75 | ALDH1A1 (0.36) | MEN1KMT2AMAOAMAOBMAPT | |
| SCHEMBL4390587 | 0.74 | — | — | |
| SCHEMBL9315430 | 0.70 | ALDH1A1 (0.33) | NPC1RAB9AMEN1KMT2ATLR4 | |
| SCHEMBL19638580 | 0.67 | EPHX2 (0.40) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL1134295 | 0.66 | MAPT (0.35) | MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3864013-A1 | THYROID HORMONE RECEPTOR AGONISTS | InventisBio Co., Ltd. (CN) | 2021-08-18 | — | — | EP | disclosed |