Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21333908 | 0.84 | MAOB (0.40) | MAOAMAOBIDO1 | |
| SCHEMBL28499236 | 0.80 | TSHR (0.35) | ALDH1A1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6710688 | 0.79 | TSHR (0.32) | ALDH1A1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4757678 | 0.79 | KMT2A (0.35) | ALDH1A1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5284629 | 0.78 | ALDH1A1 (0.39) | ALDH1A1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2331142 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL23748559 | 0.75 | NPC1 (0.33) | MEN1KMT2AMAPTMAOAMAOB | |
| SCHEMBL1134295 | 0.72 | MAPT (0.35) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL9199753 | 0.71 | ALDH1A1 (0.34) | ALDH1A1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL19638580 | 0.70 | EPHX2 (0.40) | ALDH1A1TSHRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002325-A1 | PYRROLO[2,3-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | PLEXXIKON, INC. (US) | 2007-01-04 | — | — | WO | disclosed |