⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163433 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL9425516 | 0.83 | — | — | |
| Fluoride SCHEMBL27850618 | 0.83 | — | — | |
| Formic Acid SCHEMBL3423113 | 0.82 | — | — | |
| Benzene SCHEMBL28179804 | 0.80 | HSP90AA1 (0.36) | — | |
| Trifluoroacetic Acid SCHEMBL25401305 | 0.75 | L3MBTL1 (0.38) | — | |
| Trifluoromethanesulfonic Acid SCHEMBL30805625 | 0.74 | CFTR (0.33) | — | |
| Pyrimidine SCHEMBL28940749 | 0.73 | HSP90AA1 (0.34) | — | |
| Thiophene SCHEMBL27622194 | 0.71 | ALDH1A1 (0.32) | — | |
| Serine SCHEMBL312921 | 0.70 | ARG1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12545652-B2 | Crystalline forms of a TYK2 inhibitor | SAREUM LIMITED (GB) | 2026-02-10 | — | — | US | disclosed |
| EP-3864009-B1 | TYK2 KINASE INHIBITORS | SAREUM LTD (GB) | 2025-02-19 | — | — | EP | disclosed |
| US-12187716-B2 | TYK2 kinase inhibitors | SAREUM LIMITED (GB) | 2025-01-07 | — | — | US | disclosed |
| US-20230159473-A1 | CRYSTALLINE FORMS OF A TYK2 INHIBITOR | SAREUM LIMITED (GB) | 2023-05-25 | — | — | US | disclosed |
| EP-4132649-A1 | CRYSTALLINE FORMS OF A TYK2 INHIBITOR | Sareum Limited (GB) | 2023-02-15 | — | — | EP | disclosed |
| US-20210387981-A1 | TYK2 KINASE INHIBITORS | SAREUM LIMITED (GB) | 2021-12-16 | — | — | US | disclosed |
| EP-3864009-A1 | TYK2 KINASE INHIBITORS | Sareum Limited (GB) | 2021-08-18 | — | — | EP | disclosed |