Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19543140 | 0.89 | LMNA (0.41) | LMNAALDH1A1 | |
| SCHEMBL19542922 | 0.84 | LMNA (0.38) | LMNAALDH1A1 | |
| SCHEMBL19542917 | 0.84 | LMNA (0.43) | LMNAALDH1A1 | |
| SCHEMBL23749287 | 0.83 | ALDH1A1 (0.37) | ALDH1A1PIK3CD | |
| SCHEMBL24929323 | 0.83 | LMNA (0.39) | LMNA | |
| SCHEMBL21106049 | 0.83 | PIK3CD (0.32) | LMNAPIK3CD | |
| SCHEMBL14241231 | 0.82 | LMNA (0.36) | LMNA | |
| SCHEMBL21142675 | 0.82 | MMP1 (0.31) | — | |
| SCHEMBL21439916 | 0.80 | LMNA (0.35) | LMNA | |
| SCHEMBL15179289 | 0.80 | LMNA (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158899-A1 | ELONGATION FACTOR 1-ALPHA INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-12 | — | — | WO | disclosed |