Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22007501 | 0.83 | TSHR (0.36) | LMNATSHR | |
| SCHEMBL23748577 | 0.83 | LMNA (0.38) | LMNA | |
| SCHEMBL21142675 | 0.81 | MMP1 (0.31) | — | |
| SCHEMBL21078041 | 0.78 | LMNA (0.36) | LMNATSHR | |
| SCHEMBL7856150 | 0.75 | FDPS (0.36) | — | |
| SCHEMBL29349110 | 0.75 | LMNA (0.32) | LMNA | |
| SCHEMBL21439916 | 0.74 | LMNA (0.35) | LMNA | |
| SCHEMBL15179289 | 0.74 | LMNA (0.35) | LMNA | |
| SCHEMBL23559970 | 0.73 | — | — | |
| SCHEMBL23749287 | 0.73 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009618-A1 | BICYCLIC PGDH INHIBITORS AND METHODS OF MAKING AND USING | EPIRIUM BIO, INC. (US) | 2023-02-02 | — | — | WO | disclosed |