SCHEMBL23748690

SCHEMBL23748690

CCCCCOc1ccc(F)c(C(=O)O)c1OC

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.49
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
PLA2G2D Q9UNK4 1/20 0.43
SMPD1 P17405 3/20 0.43
S1PR3 Q99500 1/20 0.43
PTPN11 Q06124 1/20 0.43
PPARA Q07869 1/20 0.43
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42
FABP4 P15090 1/20 0.42
FABP5 Q01469 1/20 0.42
PLA2G4B P0C869 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4501917 0.80 HTT (0.51) ALDH1A1FABP4
SCHEMBL12470199 0.75 KDM4E (0.50) ALDH1A1TSHRFABP4
SCHEMBL17712592 0.75 PTPN1 (0.43) PTPN1FABP4
SCHEMBL28214627 0.74 PTPN11 (0.54) PTPN1ALDH1A1HPGDS1PR3PTPN11
SCHEMBL17285548 0.74 CA9 (0.46) PTPN1THRATHRBFABP4FABP5
SCHEMBL24136176 0.74 PTPN1 (0.59) PTPN1PPARATP53TSHR
SCHEMBL23748658 0.74 ALDH1A1 (0.48) ALDH1A1HPGDS1PR3PTPN11TP53
SCHEMBL9440011 0.74 THRA (0.66) ALDH1A1HPGDPLA2G2DPTPN11THRA
SCHEMBL23748636 0.74 CA12 (0.66) PTPN1PPARATP53TSHRPLA2G4B
SCHEMBL8091128 0.73 CNR2 (0.53) PTPN1SMPD1S1PR3PTPN11PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473249-B2 Aromatic compounds and pharmaceutical uses thereof BASF AS (NO) 2025-11-18 US disclosed
US-20210380521-A1 AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF BASF AS (NO) 2021-12-09 US disclosed
US-20210380521-A1 AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF BASF AS (NO) 2021-12-09 US disclosed
EP-3864001-A1 ROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF BASF AS (NO) 2021-08-18 EP disclosed
CN-113166024-A Aromatic compounds and their medical use 巴斯夫股份公司 2021-07-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12473249-B2 Aromatic compounds and pharmaceutical uses thereof GLS2, FFAR3, SLC10A1 PTPN1 1405/4885ALDH1A1 530/4885HPGD 1388/4885
US-20210380521-A1 AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF GLS2, FFAR3, SLC10A1 PTPN1 1405/4885ALDH1A1 530/4885HPGD 1388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.