Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.34 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749121 | 0.97 | DHODH (0.38) | DHODHALDH1A1MEN1KMT2AHTT | |
| Potassium Ion SCHEMBL23749110 | 0.90 | MEN1 (0.40) | DHODHALDH1A1MEN1KMT2AHTT | |
| SCHEMBL23749170 | 0.87 | MEN1 (0.40) | DHODHALDH1A1MEN1KMT2AHTT | |
| Potassium Ion SCHEMBL23749139 | 0.85 | HTR2A (0.33) | DHODH | |
| SCHEMBL11243398 | 0.84 | FUT7 (0.46) | ALDH1A1MEN1KMT2AHTTP2RY2 | |
| SCHEMBL1355937 | 0.84 | FUT7 (0.43) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL11239209 | 0.84 | FUT7 (0.46) | ALDH1A1MEN1KMT2AHTTP2RY2 | |
| SCHEMBL8578532 | 0.84 | FUT7 (0.46) | ALDH1A1MEN1KMT2AHTTP2RY2 | |
| SCHEMBL11230120 | 0.84 | FUT7 (0.46) | ALDH1A1MEN1KMT2AHTTP2RY2 | |
| SCHEMBL4653223 | 0.84 | FUT7 (0.46) | ALDH1A1MEN1KMT2AHTTP2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3864963-A1 | OILY SUSPENSION AGROCHEMICAL COMPOSITION | Kumiai Chemical Industry Co., Ltd. (JP) | 2021-08-18 | — | — | EP | disclosed |