Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 10/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850491 | 0.87 | FTO (0.60) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL23749240 | 0.87 | ALDH1A1 (0.43) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL23749242 | 0.87 | MAPT (0.39) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL23002141 | 0.86 | FTO (0.55) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL2407192 | 0.85 | FTO (0.59) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL6685820 | 0.84 | FTO (0.53) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL23749243 | 0.84 | MEN1 (0.45) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL20832 | 0.83 | ALDH1A1 (0.60) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL9427960 | 0.82 | FTO (0.59) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL3730178 | 0.82 | FTO (0.59) | FTOMAPTHPGDMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230104281-A1 | FLUORESCENT RHODAMINE DYES WITH ENHANCED CELL PERMEABILITY | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E. V. (DE) | 2023-04-06 | — | — | US | disclosed |
| EP-3865544-A1 | FLUORESCENT RHODAMINE DYES WITH ENHANCED CELL PERMEABILITY | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-08-18 | — | — | EP | disclosed |