SCHEMBL23749243

SCHEMBL23749243

CC(C)(C)OC(=O)c1cccc2c1C(=O)OC21c2ccc(O[Si](C)(C)C(C)(C)C)cc2Oc2cc(O[Si](C)(C)C(C)(C)C)ccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
MAPT P10636 2/20 0.45
HTT P42858 2/20 0.45
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 2/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45
CYP3A4 P08684 1/20 0.41
GSTP1 P09211 1/20 0.39
FTO Q9C0B1 6/20 0.36
CA12 O43570 4/20 0.36
CA1 P00915 4/20 0.36
CA9 Q16790 4/20 0.36
HPGD P15428 2/20 0.36
CYP2C19 P33261 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
SMAD3 P84022 1/20 0.36
PRMT1 Q99873 1/20 0.36
ACE2 Q9BYF1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23749244 0.89 CA12 (0.34) MEN1MAPTHTTKMT2AALDH1A1
SCHEMBL23749239 0.87 MEN1 (0.33) MEN1MAPTHTTKMT2AALDH1A1
SCHEMBL23749241 0.84 FTO (0.53) MEN1MAPTHTTKMT2AALDH1A1
SCHEMBL23749240 0.82 ALDH1A1 (0.43) MEN1MAPTHTTKMT2AALDH1A1
SCHEMBL7557815 0.80 CYP3A4 (0.42) MEN1MAPTHTTKMT2AALDH1A1
SCHEMBL30829200 0.79 CYP3A4 (0.65) MEN1MAPTHTTKMT2AALDH1A1
SCHEMBL27392150 0.79 CYP3A4 (0.65) MEN1MAPTHTTKMT2AALDH1A1
SCHEMBL4230526 0.76 ALDH1A1 (0.53) MEN1MAPTHTTKMT2AALDH1A1
SCHEMBL1029702 0.74 ALDH1A1 (0.67) MEN1MAPTHTTKMT2AALDH1A1
SCHEMBL23749242 0.74 MAPT (0.39) MEN1MAPTHTTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230104281-A1 FLUORESCENT RHODAMINE DYES WITH ENHANCED CELL PERMEABILITY MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E. V. (DE) 2023-04-06 US disclosed
EP-3865544-A1 FLUORESCENT RHODAMINE DYES WITH ENHANCED CELL PERMEABILITY Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2021-08-18 EP disclosed