SCHEMBL23752181

SCHEMBL23752181

OCCOc1c(F)cccc1-c1ccc(F)cc1F

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 3/20 0.46
FEN1 P39748 3/20 0.46
MAPK14 Q16539 4/20 0.38
GCK P35557 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
DHPS P49366 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PDK2 Q15119 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
SYK P43405 1/20 0.34
GRM5 P41594 1/20 0.34
AKR1A1 P14550 1/20 0.34
AKR1B1 P15121 1/20 0.34
PTGER1 P34995 1/20 0.34
F10 P00742 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9060947 0.79 ALOX5AP (0.39) ALOX5APFEN1GCKFFAR4MEN1
SCHEMBL3267322 0.78 ALDH1A1 (0.46) ALOX5APFEN1GCKFFAR4DHPS
SCHEMBL26625639 0.70 ALDH1A1 (0.49)
SCHEMBL24264062 0.70 ALDH1A1 (0.39) ALOX5APFEN1GCKDHPSMEN1
SCHEMBL21595767 0.70 KMT2A (0.42) KMT2A
SCHEMBL20989248 0.70 NFE2L2 (0.48) ALOX5APFEN1MAPK14PDK2
SCHEMBL3864712 0.70 ALOX5AP (0.44) ALOX5APFEN1MEN1KMT2A
SCHEMBL9060963 0.69 FFAR4 (0.40) ALOX5APFEN1FFAR4DHPSPDK2
SCHEMBL9634005 0.68 L3MBTL1 (0.49) ALOX5APFEN1GCKFFAR4DHPS
SCHEMBL13824211 0.68 GCGR (0.36) MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed