Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | DHPS | P49366 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633992 | 0.84 | KDM4E (0.52) | L3MBTL1TDP1TSHRSMN1; SMN2KCNH2 | |
| SCHEMBL9632436 | 0.83 | L3MBTL1 (0.49) | L3MBTL1TDP1TSHRSMN1; SMN2KCNH2 | |
| SCHEMBL2035810 | 0.80 | L3MBTL1 (0.53) | L3MBTL1TDP1TUBB1SMN1; SMN2KMT2A | |
| SCHEMBL10629744 | 0.79 | TSHR (0.44) | L3MBTL1TDP1DHPSTSHRTUBB1 | |
| SCHEMBL3267322 | 0.79 | ALDH1A1 (0.46) | L3MBTL1DHPSTSHRFFAR4GCK | |
| SCHEMBL21246942 | 0.79 | L3MBTL1 (0.43) | L3MBTL1TDP1SMN1; SMN2FFAR4KMT2A | |
| SCHEMBL1007504 | 0.78 | GRM2 (0.43) | L3MBTL1TDP1ALDH1A1ALOX5APFEN1 | |
| SCHEMBL2089982 | 0.77 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL8897368 | 0.77 | LMNA (0.52) | L3MBTL1TDP1TSHRSMN1; SMN2KCNH2 | |
| SCHEMBL29669870 | 0.77 | NFE2L2 (0.50) | L3MBTL1TDP1SMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331943-B1 | PHENOXYETHYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND COMPOSITION FOR EXHIBITING EXCELLENT ALPHA-1-BLOCKING ACTIVITY CONTAINING THE SAME | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1992-06-17 | — | — | EP | disclosed |
| US-4971990-A | HYPOTENSIVE AGENTS, DYSUREA | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0331943-A1 | Phenoxyethylamine derivatives, process for preparing the same, and composition for exhibiting excellent alpha-1-blocking activity containing the same | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1989-09-13 | — | — | EP | disclosed |