SCHEMBL23753971

SCHEMBL23753971

CCc1cc2cccc(CC)c2nc1NN

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 6/20 0.38
▸ ATM Q13315 1/20 0.38
▸ PARP1 P09874 1/20 0.36
▸ TLR8 Q9NR97 1/20 0.35
▸ KCNH2 Q12809 2/20 0.35
▸ SCN5A Q14524 2/20 0.35
▸ ELANE P08246 1/20 0.35
▸ GABRA1 P14867 2/20 0.34
▸ GABRB2 P47870 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ CACNA1C Q13936 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ DAO P14920 1/20 0.33
▸ PIK3CD O00329 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12565004 0.78 TERT (0.50) TERTATMPARP1TLR8KCNH2
SCHEMBL10496032 0.70 KMT2A (0.44) TERTATMPARP1KCNH2SCN5A
SCHEMBL28827733 0.70 KMT2A (0.53) TERTATMPARP1GABRA1GABRB2
SCHEMBL7051195 0.68 MCHR1 (0.54) —
SCHEMBL25520946 0.68 GABRA1 (0.44) TERTATMPARP1GABRA1GABRB2
SCHEMBL15119498 0.68 MEN1 (0.53) TERTPARP1GABRA1GABRB2MEN1
SCHEMBL27416308 0.68 PARP1 (0.61) TERTPARP1
SCHEMBL1889250 0.66 MEN1 (0.43) ATMMEN1KMT2AMAPTPIK3CD
SCHEMBL19552354 0.66 ALDH1A1 (0.42) GABRA1GABRB2MAPT
SCHEMBL9909149 0.66 METAP2 (0.55) PARP1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4103946-B1 IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME IMMUNDIAGNOSTIK AG (DE) 2024-03-13 — — EP claimed
US-20230109016-A1 IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME IMMUNDIAGNOSTIK AG (DE) 2023-04-06 — — US claimed
EP-4103946-A1 IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME Immundiagnostik AG (DE) 2022-12-21 — — EP claimed
WO-2021160696-A1 IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME IMMUNDIAGNOSTIK AG (DE) 2021-08-19 — — WO claimed
EP-4103946-B1 IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME IMMUNDIAGNOSTIK AG (DE) 2024-03-13 — — EP disclosed
US-20230109016-A1 IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME IMMUNDIAGNOSTIK AG (DE) 2023-04-06 — — US disclosed
EP-4103946-A1 IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME Immundiagnostik AG (DE) 2022-12-21 — — EP disclosed
WO-2021160696-A1 IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME IMMUNDIAGNOSTIK AG (DE) 2021-08-19 — — WO disclosed
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