Aceneuramic Acid

Aceneuramic Acid

SCHEMBL237563

CC(=O)N[C@@H]([C@@H](O)[C@H](O)[C@H](O)CO)[C@@H](O)CC(=O)C(=O)O.Nc1ccn([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)n1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.51
GLA P06280 1/20 0.51
ST6GAL1 P15907 14/20 0.49
P2RY2 P41231 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aceneuramic Acid SCHEMBL7897261 0.92 LMNA (0.54) TSHRGLAST6GAL1P2RY2
Aceneuramic Acid SCHEMBL2302895 0.90 LMNA (0.58) TSHRGLAST6GAL1
SCHEMBL17422570 0.83 ST6GAL1 (0.56) TSHRGLAST6GAL1P2RY2
SCHEMBL3508694 0.81 P2RY2 (0.56) P2RY2
SCHEMBL4271244 0.81 P2RY2 (0.56) P2RY2
Cytarabine 5'-Phosphate SCHEMBL28003650 0.80 P2RY2 (0.55) TSHRGLAST6GAL1P2RY2
Cytarabine 5'-Phosphate SCHEMBL27855304 0.80 P2RY2 (0.55) TSHRGLAST6GAL1P2RY2
SCHEMBL10774561 0.80 P2RY2 (0.48) TSHRGLAST6GAL1P2RY2
Cytarabine 5'-Phosphate SCHEMBL28833023 0.79 P2RY2 (0.60) TSHRGLAST6GAL1P2RY2
Cytarabine 5'-Phosphate SCHEMBL28011040 0.79 P2RY2 (0.55) TSHRGLAST6GAL1P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240418701-A1 SINGLE MOLECULE IDENTIFICATION WITH A REACTIVE HETERO-NANOPORE NANJING UNIVERSITY (CN) 2024-12-19 US claimed
EP-4413379-A1 SINGLE MOLECULE IDENTIFICATION WITH A REACTIVE HETERO-NANOPORE Nanjing University (CN) 2024-08-14 EP claimed
CN-118103711-A Single molecule identification with reactive heterogeneous nanopores 南京大学 2024-05-28 CN claimed
CN-117683833-A Method for preparing nucleotide sugar from nucleoside monophosphate 山东大学 2024-03-12 CN claimed
WO-2023056960-A1 SINGLE MOLECULE IDENTIFICATION WITH A REACTIVE HETERO-NANOPORE NANJING UNIVERSITY (CN) 2023-04-13 WO claimed
WO-2021019104-A2 A PRODUCTION HOST FOR PRODUCING HUMAN MILK OLIGOSACCHARIDES BASF SE (DE) 2021-02-04 WO claimed
US-9816107-B2 Transgenic insect cells comprising a bacterial GlcNAc-6-P 2′-epimerase THE UNIVERSITY OF WYOMING (US) 2017-11-14 US claimed
US-9783838-B2 PmST3 enzyme for chemoenzymatic synthesis of alpha-2-3-sialosides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-10-10 US claimed
US-20170204381-A1 PMST1 MUTANTS FOR CHEMOENZYMATIC SYNTHESIS OF SIALYL LEWIS X COMPOUNDS UNIV CALIFORNIA (US) 2017-07-20 US claimed
US-20160015617-A1 Compositions and Methods for Reducing Skin Pigmentation YALE UNIVERSITY 2016-01-21 US claimed
US-20030130175-A1 Saccharide compositions, methods and apparatus for their synthesis THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2003-07-10 US claimed
EP-0481038-B1 SACCHARIDE COMPOSITIONS, METHODS AND APPARATUS FOR THEIR SYNTHESIS UNIV PENNSYLVANIA (US) 2002-10-02 EP claimed
US-20020061550-A1 Saccharide compositions, methods and apparatus for their synthesis THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2002-05-23 US claimed
US-20020045222-A1 COMPOSITIONS AND METHODS FOR SACCHARIDE SYNTHESIS ROTH STEPHEN (US) 2002-04-18 US claimed
US-6331418-B1 GLYCOSYLTRANSFERASE CAPABLE OF TRANSFERRING A PRESELECTED SACCHARIDE UNIT TO AN ACCEPTOR MOIETY IS ISOLATED BY CONTACTING ACCEPTOR MOIETY WITH GLYCOSYLTRANSFERASE; CATALYZING REACTION BETWEEN DONOR AND ACCEPTOR, REPEATING NEOSE TECHNOLOGIES, INC. 2001-12-18 US claimed
US-6187754-B1 Sialyl-Lewisa and sialyl-Lewisx epitode analogues GLYCOTECH CORP. 2001-02-13 US claimed
US-5874261-A Method for the purification of glycosyltransferases THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1999-02-23 US claimed
EP-0886639-A1 SIALYL-LEWISa AND SIALYL-LEWISx EPITOPE ANALOGUES GlycoTech Corp. (US) 1998-12-30 EP claimed
WO-1997047641-A1 NUCLEOTIDE SUGAR TRANSPORTERS AND USES THEREOF UNIVERSITY OF MASSACHUSETTS (US) 1997-12-18 WO claimed
WO-1997028174-A1 SIALYL-LEWISa AND SIALYL-LEWISx EPITOPE ANALOGUES NOVARTIS AG (CH) 1997-08-07 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030130175-A1 Saccharide compositions, methods and apparatus for their synthesis UGCG, OSTC, STT3A TSHR 2977/4885GLA 275/4885ST6GAL1 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.