SCHEMBL10774561

SCHEMBL10774561

Nc1ccn([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](OC(=O)C(=O)C[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)[C@H]2O)c(=O)n1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 3/20 0.48
TSHR P16473 1/20 0.48
GLA P06280 1/20 0.48
ST6GAL1 P15907 9/20 0.47
LMNA P02545 1/20 0.46
THRB P10828 1/20 0.46
MTOR P42345 1/20 0.46
MDM2 Q00987 1/20 0.46
NCOA1 Q15788 1/20 0.46
NCOA3 Q9Y6Q9 1/20 0.46
NT5E P21589 1/20 0.44
P2RY4 P51582 2/20 0.43
P2RY6 Q15077 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cytarabine 5'-Phosphate SCHEMBL27855304 0.81 P2RY2 (0.55) P2RY2TSHRGLAST6GAL1LMNA
Cytarabine 5'-Phosphate SCHEMBL28003650 0.80 P2RY2 (0.55) P2RY2TSHRGLAST6GAL1LMNA
Aceneuramic Acid SCHEMBL237563 0.80 TSHR (0.51) P2RY2TSHRGLAST6GAL1
SCHEMBL39903 0.79 P2RY2 (0.58) P2RY2TSHRGLAST6GAL1LMNA
Cytarabine 5'-Phosphate SCHEMBL28011040 0.79 P2RY2 (0.55) P2RY2TSHRGLAST6GAL1LMNA
Ribitol SCHEMBL3822628 0.79 P2RY2 (0.67) P2RY2P2RY4P2RY6
Adonitol SCHEMBL28632570 0.79 P2RY2 (0.67) P2RY2P2RY4P2RY6
Xylose SCHEMBL27858332 0.78 LMNA (0.54) P2RY2TSHRGLAST6GAL1LMNA
Cytarabine 5'-Phosphate SCHEMBL28833023 0.77 P2RY2 (0.60) P2RY2TSHRGLAST6GAL1LMNA
Cytarabine 5'-Phosphate SCHEMBL6115643 0.77 P2RY2 (0.69) P2RY2TSHRGLAST6GAL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1987003878-A1 NEW 8-SUBSTITUTED DERIVATIVES OF AN ANHYDROOCTONIC ACID, METHODS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THESE AND INTERMEDIATES Astra Läkemedel Aktiebolag (SE) 1987-07-02 WO disclosed