Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23121074 | 0.81 | CRBN (0.56) | CRBNDDB1KDM4EGAAROCK2 | |
| SCHEMBL8474128 | 0.71 | CRBN (0.43) | CRBNDDB1KDM4EGAAMAPT | |
| SCHEMBL34468957 | 0.70 | ALDH1A1 (0.45) | GAAROCK2LMNA | |
| SCHEMBL31436230 | 0.70 | CRBN (0.41) | PIK3CGCRBNDDB1KDM4EGAA | |
| SCHEMBL746783 | 0.69 | CRBN (0.66) | CRBNDDB1KDM4EGAAMAPT | |
| SCHEMBL21198026 | 0.69 | OPRM1 (0.48) | PIK3CGMAPTGRM4 | |
| SCHEMBL18096101 | 0.69 | GRM4 (0.39) | PIK3CGROCK2GRM4 | |
| SCHEMBL21517785 | 0.69 | CRBN (0.34) | CRBNDDB1 | |
| SCHEMBL21996404 | 0.69 | ALDH1A1 (0.40) | GAAROCK2LMNA | |
| SCHEMBL34468887 | 0.69 | TNKS (0.39) | PIK3CGROCK2CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106114-A1 | IDENTIFICATION OF HUMAN T2R RECEPTORS AND THE USE THEREOF TO IDENTIFY INHIBITORS (BLOCKERS) OF BITTER TASTE | SENOMYX, INC. (US) | 2011-09-01 | — | — | WO | disclosed |