Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 5/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL746783 | 0.79 | CRBN (0.66) | CRBNDDB1KDM4EGAAMAPT | |
| Hydrochloric Acid SCHEMBL31439105 | 0.78 | CRBN (0.63) | CRBNDDB1KDM4EGAAMAPT | |
| SCHEMBL27560841 | 0.78 | CRBN (0.63) | CRBNDDB1KDM4EGAAMAPT | |
| SCHEMBL11849406 | 0.78 | CRBN (0.63) | CRBNDDB1KDM4EGAAMAPT | |
| SCHEMBL8104104 | 0.78 | CRBN (0.67) | CRBNDDB1KDM4EGAAMAPT | |
| SCHEMBL10813665 | 0.76 | MEN1 (0.53) | CRBNDDB1KDM4EGAAMAPT | |
| SCHEMBL6245696 | 0.76 | CRBN (0.46) | CRBNDDB1KDM4EGAAMAPT | |
| SCHEMBL4539723 | 0.76 | CRBN (0.46) | CRBNDDB1KDM4EGAAMAPT | |
| SCHEMBL1421342 | 0.76 | DDB1 (0.46) | CRBNDDB1KDM4EGAAMAPT | |
| SCHEMBL10192194 | 0.76 | MAPT (0.53) | CRBNDDB1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004963-A | TUMOR NECROSIS FACTOR RELEASE INHIBITORS; IMMUNOMODULATORS | GRUENENTHAL GMBH (DE) | 1999-12-21 | — | — | US | disclosed |