Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31679102 | 0.99 | ADORA3 (0.54) | ADORA3ADORA2AMEN1KMT2ANPC1 | |
| SCHEMBL23758260 | 0.91 | PTPN1 (0.58) | MEN1KMT2ASMN1; SMN2HPSEMMP2 | |
| Hydrochloric Acid SCHEMBL31679076 | 0.90 | PTPN1 (0.56) | ADORA3ADORA2AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23758258 | 0.89 | KMT2A (0.62) | ADORA3ADORA2AMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL31679106 | 0.88 | KMT2A (0.61) | ADORA3ADORA2AMEN1KMT2ANPC1 | |
| SCHEMBL23758262 | 0.86 | GSK3B (0.56) | MEN1KMT2ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL23758265 | 0.85 | RAB9A (0.59) | ADORA3MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL3136907 | 0.82 | NR1H2 (0.51) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL3140919 | 0.82 | NR1H2 (0.51) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL23812443 | 0.81 | XDH (0.53) | MEN1KMT2ANPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11090289-B2 | Compositions and methods for blocking sodium channels | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2021-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11090289-B2 | Compositions and methods for blocking sodium channels | SCN3A, SCN1B, SCN2B | ADORA3 832/4885ADORA2A 1805/4885MEN1 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.