Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23528325 | 0.93 | MET (0.44) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL23528306 | 0.91 | MET (0.43) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL29570567 | 0.91 | MET (0.43) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL23528300 | 0.91 | MET (0.43) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL23528298 | 0.91 | MET (0.43) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL26527929 | 0.89 | GRIN2B (0.44) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL26528240 | 0.89 | MET (0.43) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL23528276 | 0.88 | MET (0.43) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL23528328 | 0.87 | PDE4A (0.47) | METGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL23528286 | 0.87 | MET (0.42) | METGRIN1GRIN2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11091464-B2 | Pyridazinone compounds and uses thereof | EDGEWISE THERAPEUTICS, INC. (US) | 2021-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091464-B2 | Pyridazinone compounds and uses thereof | IL6, IL1B, IL1A | MET 4212/4885GRIN1 894/4885GRIN2B 1997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.