SCHEMBL237595

SCHEMBL237595

O=C(O)CCSC(=S)SCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.61
HDAC3 O15379 3/20 0.52
HDAC4 P56524 3/20 0.52
HDAC1 Q13547 3/20 0.52
HDAC7 Q8WUI4 3/20 0.52
HDAC2 Q92769 3/20 0.52
HDAC10 Q969S8 3/20 0.52
HDAC11 Q96DB2 3/20 0.52
HDAC8 Q9BY41 3/20 0.52
HDAC6 Q9UBN7 3/20 0.52
HDAC9 Q9UKV0 3/20 0.52
HDAC5 Q9UQL6 3/20 0.52
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
IDO1 P14902 7/20 0.46
KEAP1 Q14145 1/20 0.46
CYP1A2 P05177 1/20 0.44
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2586689 0.98 CYP2C19 (0.59) CYP2C19HDAC3HDAC4HDAC1HDAC7
SCHEMBL29101443 0.91 CYP2C19 (0.51) CYP2C19HDAC3HDAC4HDAC1HDAC7
SCHEMBL29250794 0.88 HDAC3 (0.49) CYP2C19HDAC3HDAC4HDAC1HDAC7
SCHEMBL2586688 0.87 HDAC3 (0.50) CYP2C19HDAC3HDAC4HDAC1HDAC7
SCHEMBL16974387 0.87 CYP2C19 (0.57) CYP2C19HDAC3HDAC4HDAC1HDAC7
SCHEMBL16558624 0.85 HDAC3 (0.56) CYP2C19HDAC3HDAC4HDAC1HDAC7
SCHEMBL161188 0.83 CA12 (0.65) CYP2C19HDAC3HDAC4HDAC1HDAC7
SCHEMBL28381777 0.82 IDO1 (0.67) CYP2C19HDAC3HDAC4HDAC1HDAC7
SCHEMBL16552821 0.82 HDAC3 (0.63) CYP2C19HDAC3HDAC4HDAC1HDAC7
SCHEMBL16558622 0.81 IDO1 (0.52) CYP2C19IDO1CYP1A2SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
CN-116063641-B Flame-retardant lithium battery anode adhesive and preparation method thereof 深圳好电科技有限公司 2025-05-02 CN claimed
CN-119812455-A Brush polymer electrolyte, controllable preparation method and application 浙江新安化工集团股份有限公司 2025-04-11 CN claimed
CN-119243275-A Environment-friendly pulse electroplating method 深圳市金源康实业有限公司 2025-01-03 CN claimed
EP-4240578-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-12-18 EP claimed
CN-118930904-A Preparation method of UCST response Janus particles and promotion of CO2Application of cascade conversion into formic acid 江苏大学 2024-11-12 CN claimed
CN-118813135-A Functional modified fouling release type marine antifouling paint 常熟理工学院 2024-10-22 CN claimed
CN-118652627-A Catechol functionalized modified fouling release type marine antifouling paint 常熟理工学院 2024-09-17 CN claimed
CN-117758244-B Chemical nickel-plating palladium-gold solution process formula for aluminum substrate of power chip 深圳创智芯联科技股份有限公司 2024-08-23 CN claimed
CN-118326465-B Nickel-palladium-gold electroplating surface treatment liquid suitable for packaging substrate 深圳创智芯联科技股份有限公司 2024-08-06 CN claimed
US-9624317-B2 Amphiphilic macromolecular emulsifier with switchable surface activity and use thereof in preparation of polymer latex ZHEJIANG UNIVERSITY (CN) 2017-04-18 US claimed
CN-105000542-A Preparation method for graphene-carbon nano tube three-dimensional structure composite material CHONGQING INST GREEN & INTELLIGENT TECHNOLOGY CAS 2015-10-28 CN claimed
EP-2432808-B1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS NOVARTIS AG (CH) 2015-10-21 EP claimed
EP-2604332-B1 Method for preparing a functionalized nanoporous track-etched PVDF membrane with RAFT polymerization ECOLE POLYTECH (FR) 2015-07-08 EP claimed
US-20140316049-A1 AMPHIPHILIC MACROMOLECULAR EMULSIFIER WITH SWITCHABLE SURFACE ACTIVITY AND USE THEREOF IN PREPARATION OF POLYMER LATEX ZHEJIANG UNIVERSITY (CN) 2014-10-23 US claimed
EP-2604332-A1 Method for preparing a functionalized nanoporous track-etched PVDF membrane with RAFT polymerization Ecole Polytechnique (FR) 2013-06-19 EP claimed
US-8383744-B2 Actinically-crosslinkable siloxane-containing copolymers NOVARTIS AG (CH) 2013-02-26 US claimed
EP-2432808-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS Novartis AG (CH) 2012-03-28 EP claimed
WO-2010133680-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS NOVARTIS AG (CH) 2010-11-25 WO claimed
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS ALCON INC. (CH) 2010-11-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA CYP2C19 2132/4885HDAC3 3217/4885HDAC4 2931/4885
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS VCL, MACF1, CFL1 CYP2C19 4645/4885HDAC3 2787/4885HDAC4 1674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.