Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23760192 | 0.99 | MAPT (0.33) | TP53RXFP1MAPTMEN1GAA | |
| SCHEMBL23760203 | 0.94 | L3MBTL1 (0.36) | TP53RXFP1MAPTMEN1GAA | |
| SCHEMBL23760181 | 0.85 | L3MBTL1 (0.36) | TP53MAPTMEN1GAAKMT2A | |
| SCHEMBL23760205 | 0.83 | TSHR (0.31) | — | |
| SCHEMBL22036071 | 0.82 | KDM4E (0.31) | TP53MAPTMEN1GAAKMT2A | |
| SCHEMBL23760200 | 0.81 | ALOX5 (0.32) | — | |
| SCHEMBL22036074 | 0.81 | KDM4E (0.32) | MAPTMEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL23760201 | 0.79 | ALDH1A1 (0.37) | TP53RXFP1MAPTMEN1GAA | |
| SCHEMBL23760127 | 0.79 | IL1R1 (0.43) | RXFP1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL23760120 | 0.79 | WHR1 (0.38) | TP53RXFP1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630764-B1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR USE IN ELEKTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-08-18 | — | — | EP | disclosed |