Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23760190 | 0.99 | TP53 (0.33) | MAPTRXFP1TP53MEN1KMT2A | |
| SCHEMBL23760203 | 0.93 | L3MBTL1 (0.36) | MAPTRXFP1TP53MEN1KMT2A | |
| SCHEMBL23760181 | 0.84 | L3MBTL1 (0.36) | MAPTTP53MEN1KMT2AGAA | |
| SCHEMBL23760205 | 0.82 | TSHR (0.31) | — | |
| SCHEMBL22036074 | 0.81 | KDM4E (0.32) | MAPTMEN1KMT2AGAAKDM4E | |
| SCHEMBL22036071 | 0.81 | KDM4E (0.31) | MAPTTP53MEN1KMT2AGAA | |
| SCHEMBL23760200 | 0.80 | ALOX5 (0.32) | — | |
| SCHEMBL23760201 | 0.80 | ALDH1A1 (0.37) | MAPTRXFP1TP53MEN1KMT2A | |
| SCHEMBL23760127 | 0.80 | IL1R1 (0.43) | MAPTRXFP1MEN1KMT2AKDM4E | |
| SCHEMBL23760195 | 0.78 | L3MBTL1 (0.41) | MAPTRXFP1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630764-B1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR USE IN ELEKTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-08-18 | — | — | EP | disclosed |