Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17294176 | 0.98 | ALDH1A1 (0.43) | ALDH1A1KDM4ECYP3A4GABRB3OPRD1 | |
| SCHEMBL6381411 | 0.89 | LMNA (0.42) | ALDH1A1KDM4ECYP3A4GABRB3OPRD1 | |
| SCHEMBL2376039 | 0.83 | HSD17B10 (0.39) | ALDH1A1KDM4ECYP3A4GABRB3OPRD1 | |
| SCHEMBL17536132 | 0.81 | HSD17B10 (0.38) | ALDH1A1KDM4ECYP3A4GABRB3OPRD1 | |
| SCHEMBL21292107 | 0.77 | ALDH1A1 (0.36) | ALDH1A1HSD17B10LMNAKDM4CTSHR | |
| SCHEMBL8566934 | 0.74 | LMNA (0.32) | ALDH1A1KDM4ECYP3A4GABRB3OPRD1 | |
| SCHEMBL20416267 | 0.72 | IDO1 (0.43) | ALDH1A1KDM4EMAPT | |
| SCHEMBL642543 | 0.72 | TSHR (0.40) | ALDH1A1KDM4ECYP3A4GABRB3OPRD1 | |
| SCHEMBL17294174 | 0.72 | — | — | |
| SCHEMBL26644809 | 0.72 | KDM4E (0.35) | ALDH1A1KDM4ECYP3A4GABRB3OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835233-A1 | COMPOSITION AND METHOD FOR STABILIZING RADIOLABELED ORGANIC COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997001520-A1 | COMPOSITION AND METHOD FOR STABILIZING RADIOLABELED ORGANIC COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-16 | — | — | WO | disclosed |