SCHEMBL4779166

SCHEMBL4779166

CCC(CC(C)C)C1C(=O)NC(=O)NC1=O

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.35
LMNA P02545 2/20 0.33
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP3A4 P08684 1/20 0.31
GABRB3 P28472 1/20 0.31
OPRD1 P41143 1/20 0.31
GABRA2 P47869 1/20 0.31
GABRB2 P47870 1/20 0.31
KDM4C Q9H3R0 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21292103 0.87 HSD17B10 (0.34) HSD17B10LMNAALDH1A1KDM4ECYP3A4
SCHEMBL21292107 0.78 ALDH1A1 (0.36) HSD17B10LMNAALDH1A1KDM4CTSHR
SCHEMBL2376039 0.75 HSD17B10 (0.39) HSD17B10LMNAALDH1A1KDM4ECYP3A4
SCHEMBL17536132 0.74 HSD17B10 (0.38) HSD17B10LMNAALDH1A1KDM4ECYP3A4
SCHEMBL21292112 0.72 HSD17B10 (0.37) HSD17B10LMNAALDH1A1KDM4ECYP3A4
SCHEMBL642543 0.69 TSHR (0.40) HSD17B10LMNAALDH1A1KDM4ECYP3A4
SCHEMBL8614546 0.68 ALDH1A1 (0.44) HSD17B10LMNAALDH1A1KDM4ECYP3A4
SCHEMBL17536124 0.68 TSHR (0.39) HSD17B10LMNAALDH1A1KDM4CTSHR
SCHEMBL7080606 0.67 HSD17B10 (0.36) HSD17B10LMNAALDH1A1KDM4ECYP3A4
SCHEMBL17294176 0.67 ALDH1A1 (0.43) HSD17B10LMNAALDH1A1KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345767-A1 METHODS AND DEVICES FOR GENERATING CORE-SHELL DROPLETS AND PARTICLES THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-11-13 US disclosed
CN-108743549-B Self-regulating release of active pharmaceutical ingredient 阿库拉制药公司 2024-08-06 CN disclosed
US-20240108726-A1 METHODS AND COMPOSITIONS FOR SELF-REGULATED RELEASE OF ACTIVE PHARMACEUTICAL INGREDIENT ACURA PHARMACEUTICALS, INC. (US) 2024-04-04 US disclosed
US-11857629-B2 Methods and compositions for self-regulated release of active pharmaceutical ingredient ACURA PHARMACEUTICALS, INC. (US) 2024-01-02 US disclosed
WO-2023239688-A1 METHODS AND DEVICES FOR GENERATING CORE-SHELL DROPLETS AND PARTICLES THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2023-12-14 WO disclosed
US-20230330044-A1 METHODS AND COMPOSITIONS FOR INTERFERING WITH EXTRACTION OR CONVERSION OF A DRUG SUSCEPTIBLE TO ABUSE ACURA PHARMACEUTICALS INC (US) 2023-10-19 US disclosed
US-11723885-B2 Methods and compositions for interfering with extraction or conversion of a drug susceptible to abuse ACURA PHARMACEUTICALS, INC. (US) 2023-08-15 US disclosed
CN-116367864-A Controlled release filler composition and capsule containing the same R·P·谢勒技术有限公司 2023-06-30 CN disclosed
CN-116322655-A Soft gel capsule for regulating release R·P·谢勒技术有限公司 2023-06-23 CN disclosed
US-20230158008-A1 METHODS AND COMPOSITIONS FOR SELF-REGULATED RELEASE OF ACTIVE PHARMACEUTICAL INGREDIENTS ACURA PHARMACEUTICALS, INC. 2023-05-25 US disclosed
US-20120202839-A1 METHODS AND COMPOSITIONS FOR DETERRING ABUSE OF ORALLY ADMINISTERED PHARMACEUTICAL PRODUCTS ACURA PHARMACEUTICALS, INC. (US) 2012-08-09 US disclosed
EP-1993519-A2 METHODS AND COMPOSITIONS FOR DETERRING ABUSE OF ORALLY ADMINISTERED PHARMACEUTICAL PRODUCTS ACURA PHARMACEUTICALS, INC. (US) 2008-11-26 EP disclosed
US-20080152595-A1 Methods and compositions for deterring abuse of orally administered pharmaceutical products ACURA PHARMACEUTICALS, INC. 2008-06-26 US disclosed
US-20070231268-A1 Methods and compositions for deterring abuse of orally administered pharmaceutical products ACURA PHARMACEUTICALS, INC. 2007-10-04 US disclosed
WO-2007106550-A2 METHODS AND COMPOSITIONS FOR DETERRING ABUSE OF ORALLY ADMINISTERED PHARMACEUTICAL PRODUCTS ACURA PHARMACEUTICALS, INC. (US) 2007-09-20 WO disclosed
EP-1817011-A2 METHODS AND COMPOSITIONS FOR DETERRING ABUSE OF ORALLY ADMINISTERED PHARMACEUTICAL PRODUCTS ACURA PHARMACEUTICALS, INC. (US) 2007-08-15 EP disclosed
US-20060177380-A1 Methods and compositions for deterring abuse of orally administered pharmaceutical products ACURA PHARMACEUTICALS, INC. 2006-08-10 US disclosed
WO-2006058249-A9 METHODS AND COMPOSITIONS FOR DETERRING ABUSE OF ORALLY ADMINISTERED PHARMACEUTICAL PRODUCTS ACURA PHARMACEUTICALS INC (US) 2006-07-20 WO disclosed
WO-2006058249-A2 METHODS AND COMPOSITIONS FOR DETERRING ABUSE OF ORALLY ADMINISTERED PHARMACEUTICAL PRODUCTS ACURA PHARMACEUTICALS, INC. (US) 2006-06-01 WO disclosed
US-20060110327-A1 Methods and compositions for deterring abuse of orally administered pharmaceutical products ACURA PHARMACEUTICALS, INC. 2006-05-25 US disclosed