Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | PREP | P48147 | 2/20 | 0.59 |
| ▸ | DPP4 | P27487 | 2/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23760562 | 0.90 | LMNA (0.64) | LMNAKDM4EPREPDPP4DPP9 | |
| SCHEMBL21101295 | 0.83 | PREP (0.68) | LMNAKDM4EPREPDPP4DPP9 | |
| SCHEMBL22367618 | 0.82 | EGLN1 (0.45) | LMNAPREPDPP4DPP9EGLN1 | |
| SCHEMBL39557 | 0.81 | LMNA (1.00) | LMNAKDM4ECYP1A2MAPK1NPSR1 | |
| SCHEMBL30120700 | 0.81 | LMNA (1.00) | LMNAKDM4ECYP1A2MAPK1NPSR1 | |
| SCHEMBL26965961 | 0.81 | SLC2A1 (0.43) | LMNAKDM4EPREPDPP4DPP9 | |
| SCHEMBL31461294 | 0.81 | EGLN1 (0.51) | LMNAKDM4EPREPNPSR1EGLN1 | |
| SCHEMBL26965932 | 0.81 | EGLN1 (0.51) | LMNAKDM4EPREPNPSR1EGLN1 | |
| Dimethylamine SCHEMBL29039894 | 0.80 | LMNA (0.91) | LMNAKDM4ECYP1A2MAPK1NPSR1 | |
| SCHEMBL5260744 | 0.80 | LMNA (0.76) | LMNAKDM4ECYP1A2MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230147962-A1 | FIBROBLAST ACTIVATION PROTEIN LIGANDS FOR TARGETED DELIVERY APPLICATIONS | PHILOCHEM AG (CH) | 2023-05-11 | — | — | US | disclosed |
| US-20230147962-A1 | FIBROBLAST ACTIVATION PROTEIN LIGANDS FOR TARGETED DELIVERY APPLICATIONS | PHILOCHEM AG (CH) | 2023-05-11 | — | — | US | disclosed |
| EP-4019507-A1 | FIBROBLAST ACTIVATION PROTEIN LIGANDS FOR TARGETED DELIVERY APPLICATIONS | Philochem AG (CH) | 2022-06-29 | — | — | EP | disclosed |
| EP-3891138-B1 | FIBROBLAST ACTIVATION PROTEIN LIGANDS FOR TARGETED DELIVERY APPLICATIONS | PHILOCHEM AG (CH) | 2022-01-12 | — | — | EP | disclosed |
| WO-2021160825-A1 | FIBROBLAST ACTIVATION PROTEIN LIGANDS FOR TARGETED DELIVERY APPLICATIONS | PHILOCHEM AG (CH) | 2021-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230147962-A1 | FIBROBLAST ACTIVATION PROTEIN LIGANDS FOR TARGETED DELIVERY APPLICATIONS | FAP, FIBP, FGFR1 | LMNA 2916/4885KDM4E 4235/4885PREP 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.