Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 10/20 | 0.48 |
| ▸ | POLG | P54098 | 2/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23760838 | 0.84 | NT5E (0.54) | PNPPOLBHPRT1 | |
| SCHEMBL24081863 | 0.77 | FUT5 (0.55) | PNPPOLBPOLGPOLA1 | |
| SCHEMBL20879415 | 0.76 | POLG (0.64) | PNPPOLBHPRT1POLGPOLA1 | |
| SCHEMBL26208657 | 0.75 | NT5E (0.67) | POLB | |
| SCHEMBL20698981 | 0.75 | NT5E (0.57) | PNPPOLBHPRT1 | |
| SCHEMBL2922052 | 0.75 | POLB (0.61) | PNPPOLB | |
| SCHEMBL20442307 | 0.75 | POLB (0.61) | PNPPOLB | |
| SCHEMBL13619242 | 0.75 | PNP (0.79) | PNPPOLBHPRT1POLG | |
| SCHEMBL21636997 | 0.74 | NT5E (0.56) | PNPPOLBHPRT1 | |
| SCHEMBL21417496 | 0.74 | NT5E (0.56) | PNPPOLBHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512863-B1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR RNA VIRUS TREATMENT | ATEA PHARMACEUTICALS INC (US) | 2021-12-08 | — | — | EP | disclosed |