Isoorientin

Isoorientin

SCHEMBL23761

O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)c([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 7/20 1.00
KDM4E B2RXH2 6/20 1.00
APEX1 P27695 5/20 1.00
GAA P10253 5/20 1.00
POLB P06746 5/20 1.00
TDP1 Q9NUW8 4/20 1.00
MEN1 O00255 4/20 1.00
KMT2A Q03164 4/20 1.00
MAPT P10636 3/20 1.00
AKR1B1 P15121 1/20 1.00
ALDH1A1 P00352 4/20 0.83
RECQL P46063 2/20 0.83
NTSR1 P30989 1/20 0.83
THRB P10828 1/20 0.75
HSD17B10 Q99714 2/20 0.63
TNF P01375 1/20 0.63
IL2 P60568 1/20 0.63
MGAM O43451 1/20 0.62
GUSB P08236 1/20 0.62
MMP9 P14780 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoorientin SCHEMBL18605974 1.00 L3MBTL1 (1.00) L3MBTL1KDM4EAPEX1GAAPOLB
Isoorientin SCHEMBL29350057 1.00 L3MBTL1 (1.00) L3MBTL1KDM4EAPEX1GAAPOLB
Isoorientin SCHEMBL30098358 1.00 L3MBTL1 (1.00) L3MBTL1KDM4EAPEX1GAAPOLB
Isoorientin SCHEMBL1706772 1.00 L3MBTL1 (1.00) L3MBTL1KDM4EAPEX1GAAPOLB
Isoorientin SCHEMBL29687259 1.00 L3MBTL1 (1.00) L3MBTL1KDM4EAPEX1GAAPOLB
Isoorientin SCHEMBL14076164 1.00 L3MBTL1 (1.00) L3MBTL1KDM4EAPEX1GAAPOLB
Isoorientin SCHEMBL10307522 1.00 L3MBTL1 (1.00) L3MBTL1KDM4EAPEX1GAAPOLB
Isoorientin SCHEMBL22878053 1.00 L3MBTL1 (1.00) L3MBTL1KDM4EAPEX1GAAPOLB
Isoorientin SCHEMBL22785963 1.00 L3MBTL1 (1.00) L3MBTL1KDM4EAPEX1GAAPOLB
Isovitexin SCHEMBL20870220 0.91 L3MBTL1 (1.00) L3MBTL1KDM4EAPEX1GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1468 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122074542-A Application of isoorientin in preparation of quencher for inhibiting serratia liquefaciens quorum sensing system 2026-05-26 CN claimed
CN-122081031-A Method for improving stability of flavone in tartary buckwheat wine 2026-05-26 CN claimed
US-20260077276-A1 METHODS TO CONVERT THCA INTO THC NATURAL EXTRACTION SYS LLC (US) 2026-03-19 US claimed
US-12491228-B2 Fine bamboo powder and preparation method therefor and use thereof SICHUAN SENLONG BIO-TECH CO., LTD. (CN) 2025-12-09 US claimed
US-20250351855-A1 TASTE OF CONSUMABLES THE PRODUCT MAKERS (AUSTRALIA) PTY LTD (AU) 2025-11-20 US claimed
US-12448610-B2 Preparation of glycosyltransferase UGT76G1 mutant and use thereof CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2025-10-21 US claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
CN-116349698-B Application of rice leaf extract in inhibiting plant growth 中国科学院植物研究所 2025-06-17 CN claimed
CN-116349705-B Application of rice leaf extract in inhibiting postharvest bacteria of fruits and vegetables 中国科学院植物研究所 2025-06-17 CN claimed
CN-116349706-B Application of rice leaf extract in pest killing 中国科学院植物研究所 2025-06-17 CN claimed
US-20050226948-A1 Methods for enhancing the transport of glucose into muscle TECHNICAL SOURCING INTERNATIONAL, INC. 2005-10-13 US claimed
WO-2005084323-A2 COMPOSITIONS OF BIO-ACTIVE COMPOUNDS FROM FENUGREEK SEED AND METHODS FOR PRODUCING SAME TECHNICAL SOURCING INTERNATIONAL, INC. (US) 2005-09-15 WO claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
US-20040002423-A1 Remedies TAKARA BIO INC. (JP) 2004-01-01 US claimed
US-20030203857-A1 Polyphenols, derivatives, and/or salts as therapeutic or prophylactic agents, useful for treating a disease requiring enhancement for growth factor such as nerve growth factor and hepatocyte growth factor TAKARA BIO INC. (JP) 2003-10-30 US claimed
US-20030166583-A1 Such as epicatechin coadministered with retinoic acid; bioavailability HU, OLIVER YOA-PU (TW) 2003-09-04 US claimed
CN-1436074-A Remedies TAKARA BIO INC (JP) 2003-08-13 CN claimed
CN-1422159-A Therapeutic agents TAKARA SHUZO CO (JP) 2003-06-04 CN claimed
EP-1283037-A1 REMEDIES TAKARA BIO INC. (JP) 2003-02-12 EP claimed
EP-1277473-A1 REMEDIES TAKARA BIO INC. (JP) 2003-01-22 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050226948-A1 Methods for enhancing the transport of glucose into muscle GYS1, SLC2A3, MUSK L3MBTL1 2198/4885KDM4E 4227/4885APEX1 3694/4885
US-20030166583-A1 Such as epicatechin coadministered with retinoic acid; bioavailability CYP51A1, CYP2E1, CYP7A1 L3MBTL1 4873/4885KDM4E 4575/4885APEX1 3589/4885
US-20260077276-A1 METHODS TO CONVERT THCA INTO THC CNR2, CNR1, FAAH L3MBTL1 4854/4885KDM4E 1653/4885APEX1 4445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.