Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27471328 | 0.84 | CD274 (0.57) | GAAKDM4ETSHRALDH1A1TDP1 | |
| SCHEMBL9462879 | 0.83 | ERCC1 (0.59) | GAAALOX15KDM4ECYP3A4TSHR | |
| SCHEMBL3721209 | 0.79 | TRPV1 (0.69) | GAAALOX15KDM4ECYP3A4TSHR | |
| SCHEMBL29213350 | 0.78 | GAA (0.49) | GAAALOX15KDM4ECYP3A4TSHR | |
| SCHEMBL29213354 | 0.78 | GAA (0.49) | GAAALOX15KDM4ECYP3A4TSHR | |
| SCHEMBL30903305 | 0.78 | GAA (0.49) | GAAALOX15KDM4ECYP3A4TSHR | |
| SCHEMBL11673049 | 0.78 | ALDH1A1 (0.62) | KDM4EALDH1A1TDP1MAPK1LDHA | |
| SCHEMBL6237220 | 0.77 | LDHA (0.57) | RAB9AALDH1A1LDHA | |
| SCHEMBL490932 | 0.77 | LDHA (0.76) | GAAALOX15KDM4ECYP3A4TSHR | |
| SCHEMBL28049334 | 0.77 | LDHA (0.57) | RAB9AALDH1A1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106114-A1 | IDENTIFICATION OF HUMAN T2R RECEPTORS AND THE USE THEREOF TO IDENTIFY INHIBITORS (BLOCKERS) OF BITTER TASTE | SENOMYX, INC. (US) | 2011-09-01 | — | — | WO | disclosed |
| CN-1088083-A | Cosmetic composition | UNILEVER NV (NL) | 1994-06-22 | — | — | CN | disclosed |