Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237220 | 1.00 | LDHA (0.57) | LDHAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14971737 | 0.87 | ALDH1A1 (0.51) | LDHAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2716941 | 0.87 | ALDH1A1 (0.51) | LDHAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9201087 | 0.85 | MAOA (0.62) | — | |
| SCHEMBL8804579 | 0.85 | MAOA (0.62) | — | |
| SCHEMBL28246898 | 0.84 | LDHA (0.54) | LDHAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5967428 | 0.84 | MAOA (0.61) | — | |
| SCHEMBL29176908 | 0.83 | EPHX2 (0.53) | ALDH1A1NPC1RAB9ASMN1; SMN2CASR | |
| SCHEMBL24446771 | 0.81 | ANPEP (0.59) | LDHAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17666275 | 0.81 | MAOA (0.65) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263519-A | Compositions and methods for treating cancer | Univ Virginia Patent Found | 2016-01-20 | — | — | CN | disclosed |