SCHEMBL23763567

SCHEMBL23763567

CC(C)(C)c1ccc2c(c1)c1c3c4c(c5cc(C(C)(C)C)ccc5n4c4nc5c(C#N)cc(C(C)(C)C)cc5n34)c3c1n2c1nc2c(C#N)cc(C(C)(C)C)cc2n31

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CSNK1D P48730 1/20 0.31
CSNK1G2 P78368 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23763732 0.83 HTR1D (0.31)
SCHEMBL23763568 0.82 ALOX5AP (0.35)
SCHEMBL23763731 0.77 HTR1D (0.33)
SCHEMBL23763729 0.76
SCHEMBL23763557 0.76 HTR1D (0.34)
SCHEMBL23763561 0.75 PGR (0.30)
SCHEMBL23763575 0.74 STAT3 (0.35)
SCHEMBL23763599 0.73
SCHEMBL23763499 0.73 ALDH1A1 (0.39)
SCHEMBL23763425 0.71 NR1H4 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3865486-A1 HETEROCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE HETEROCYCLIC COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2021-08-18 EP disclosed