SCHEMBL23763568

SCHEMBL23763568

CC(C)(C)c1ccc2c(c1)c1c3c4c(c5cc(C(C)(C)C)ccc5n4c4nc5c(F)cc(C(C)(C)C)cc5n34)c3c1n2c1nc2c(F)cc(C(C)(C)C)cc2n31

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.35
KCNH2 Q12809 1/20 0.33
HTR1D P28221 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23763732 0.86 HTR1D (0.31) HTR1D
SCHEMBL23763567 0.82 CSNK1D (0.31)
SCHEMBL23763731 0.80 HTR1D (0.33) KCNH2HTR1D
SCHEMBL23763729 0.79
SCHEMBL23763557 0.79 HTR1D (0.34) KCNH2HTR1D
SCHEMBL23763561 0.78 PGR (0.30) HTR1D
SCHEMBL23763599 0.76
SCHEMBL23763499 0.75 ALDH1A1 (0.39)
SCHEMBL23763425 0.74 NR1H4 (0.38)
SCHEMBL23763575 0.74 STAT3 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3865486-A1 HETEROCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE HETEROCYCLIC COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2021-08-18 EP disclosed