Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | RORA | P35398 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | RORB | Q92753 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23763628 | 0.92 | PTGER4 (0.34) | ALDH1A1KCNH2MAPTKDM4EPGR | |
| SCHEMBL23763499 | 0.92 | ALDH1A1 (0.39) | LMNAALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL23763626 | 0.87 | KDM4E (0.38) | LMNAALDH1A1TP53SMN1; SMN2ADORA2A | |
| SCHEMBL23763557 | 0.83 | HTR1D (0.34) | KCNH2PGRRORARORCRORB | |
| SCHEMBL22062719 | 0.82 | ALDH1A1 (0.36) | LMNAALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL23763731 | 0.81 | HTR1D (0.33) | KCNH2PGRRORARORCRORB | |
| SCHEMBL22088273 | 0.81 | ALDH1A1 (0.34) | LMNAALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL23763539 | 0.80 | SMN1; SMN2 (0.35) | LMNAALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL23763733 | 0.79 | PLK4 (0.36) | LMNAALDH1A1TP53SMN1; SMN2ADORA2A | |
| SCHEMBL23763423 | 0.78 | CYP19A1 (0.34) | ALDH1A1TP53SMN1; SMN2ADORA2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865486-A1 | HETEROCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE HETEROCYCLIC COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2021-08-18 | — | — | EP | disclosed |