Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | FES | P07332 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23763731 | 0.89 | HTR1D (0.33) | PDE2APDE10APGRRORARORC | |
| SCHEMBL23763499 | 0.86 | ALDH1A1 (0.39) | KIF11PDE2ATP53SMN1; SMN2ADORA2A | |
| SCHEMBL23763423 | 0.83 | CYP19A1 (0.34) | CDK2ALKKIF11TP53SMN1; SMN2 | |
| SCHEMBL23763431 | 0.81 | FLT3 (0.36) | FLT3PGRRORARORCRORB | |
| SCHEMBL18805412 | 0.81 | SCN10A (0.40) | PDE2APDE10AMAPTALDH1A1MEN1 | |
| SCHEMBL23763598 | 0.79 | LMNA (0.34) | LCKSRCTP53SMN1; SMN2ADORA2A | |
| SCHEMBL23763430 | 0.79 | PDE10A (0.38) | LCKKDRJAK3CLK4PDE2A | |
| SCHEMBL23763557 | 0.79 | HTR1D (0.34) | KIF11PDE2APDE10APGRRORA | |
| SCHEMBL23763628 | 0.78 | PTGER4 (0.34) | MAPTALDH1A1MEN1GAAKMT2A | |
| SCHEMBL19735270 | 0.78 | KDM4E (0.43) | PLK4CHEK1AURKACHUKPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865486-A1 | HETEROCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE HETEROCYCLIC COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2021-08-18 | — | — | EP | disclosed |