Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | TP53 | P04637 | 6/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23763604 | 0.88 | KDM4E (0.35) | SMN1; SMN2TP53ALDH1A1LMNAPOLB | |
| SCHEMBL23763499 | 0.87 | ALDH1A1 (0.39) | SMN1; SMN2TP53ADORA2AALDH1A1LMNA | |
| SCHEMBL22088875 | 0.81 | ALDH1A1 (0.34) | SMN1; SMN2TP53ADORA2AALDH1A1LMNA | |
| SCHEMBL22063058 | 0.81 | ALDH1A1 (0.39) | SMN1; SMN2TP53ADORA2AALDH1A1LMNA | |
| SCHEMBL23763598 | 0.80 | LMNA (0.34) | SMN1; SMN2TP53ADORA2AALDH1A1LMNA | |
| SCHEMBL23763557 | 0.78 | HTR1D (0.34) | — | |
| SCHEMBL23763733 | 0.77 | PLK4 (0.36) | SMN1; SMN2TP53ADORA2AALDH1A1LMNA | |
| SCHEMBL23763731 | 0.76 | HTR1D (0.33) | — | |
| SCHEMBL25881030 | 0.75 | PGR (0.33) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL23763628 | 0.74 | PTGER4 (0.34) | ALDH1A1MAPTKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865486-A1 | HETEROCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE HETEROCYCLIC COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2021-08-18 | — | — | EP | disclosed |