SCHEMBL237637

SCHEMBL237637

Cc1c([SiH3])ccc(Cl)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.35
CES1 P23141 2/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP2A6 P11509 1/20 0.31
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL918736 0.81 CES1 (0.38) CES1ALDH1A1
SCHEMBL900037 0.77 ALDH1A1 (0.42) CYP3A4MAPK1CES1ALDH1A1CYP2A6
SCHEMBL38745 0.75 CYP3A4 (0.46) CYP3A4MAPK1CES1CYP2A6AHR
SCHEMBL27803122 0.72 CYP3A4 (0.39) CYP3A4MAPK1CES1ALDH1A1CYP2A6
SCHEMBL258271 0.72 CYP3A4 (0.39) CYP3A4MAPK1CES1ALDH1A1CYP2A6
SCHEMBL10583579 0.72 CYP3A4 (0.34) CYP3A4MAPK1CES1ALDH1A1CYP2A6
SCHEMBL15301875 0.69 CYP3A4 (0.31) CYP3A4MAPK1
SCHEMBL2100525 0.69 CYP3A4 (0.31) CYP3A4MAPK1
SCHEMBL2103374 0.69 CYP3A4 (0.33) CYP3A4MAPK1ALDH1A1
SCHEMBL2102662 0.69 CYP3A4 (0.31) CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025233670-A1 HYDROPHOBIC BINDER COMPOSITION AND A PROCESS FOR ITS PREPARATION CHEMTECH SPECIALITY INDIA PVT. LTD. (IN) 2025-11-13 WO claimed
WO-2024007909-A1 ETCHING COMPOSITION, ETCHING METHOD AND APPLICATION 上海集成电路材料研究院有限公司 2024-01-11 WO claimed
US-11515538-B2 In-situ polymerization to protect lithium metal electrodes GM Global Technology Operations LLC (US) 2022-11-29 US claimed
WO-2025233670-A1 HYDROPHOBIC BINDER COMPOSITION AND A PROCESS FOR ITS PREPARATION CHEMTECH SPECIALITY INDIA PVT. LTD. (IN) 2025-11-13 WO disclosed
US-20240060891-A1 A METHOD FOR DETECTING AN ANALYTE PSYROS DIAGNOSTICS LIMITED (GB) 2024-02-22 US disclosed
US-11886112-B2 Curable composition, near infrared absorber, film, near infrared cut filter, solid-state imaging element, image display device, and infrared sensor FUJIFILM CORPORATION (JP) 2024-01-30 US disclosed
WO-2024007909-A1 ETCHING COMPOSITION, ETCHING METHOD AND APPLICATION 上海集成电路材料研究院有限公司 2024-01-11 WO disclosed
EP-4264266-A1 A METHOD FOR DETECTING AN ANALYTE Psyros Diagnostics Limited (GB) 2023-10-25 EP disclosed
US-11708479-B2 Resin composition, film, near infrared cut filter, infrared transmitting filter, solid image pickup element, image display device, infrared sensor, and camera module FUJIFILM CORPORATION (JP) 2023-07-25 US disclosed
EP-3444293-B1 METHOD FOR PRODUCING ORGANIC POLYSILANE NIPPON SODA CO (JP) 2023-06-28 EP disclosed
US-11655386-B2 Three-dimensional inkjet printing using ring-opening metathesis polymerization STRATASYS LTD. (IL) 2023-05-23 US disclosed
US-20080139834-A1 Method of Making Phenyl-Containing Chlorosilanes with Aliphatic or Cycloparaffinic Hydrocarbon Solvents DOW CORNING CORPORATION (US) 2008-06-12 US disclosed
US-7351847-B2 Grignard processes with increased content of diphenylchlorosilanes DOW CORNING CORPORATION (US) 2008-04-01 US disclosed
US-20080070193-A1 Dental Composition Containing Unsaturated Carbosilane Containing Components 3M DEUTSCHLAND GMBH (DE) 2008-03-20 US disclosed
US-7344811-B2 Polysilane-based charge transport materials SAMSUNG ELECTRONIC CO., LTD. (KR) 2008-03-18 US disclosed
US-20070090362-A1 Thin film transistor, method of manufacturing the same and flat panel display having the thin film transistor SAMSUNG SDI CO., LTD. (KR) 2007-04-26 US disclosed
US-20070066826-A1 Grignard processes with improved yields of diphenylchlorosilanes as products DOW CORNING CORPORATION 2007-03-22 US disclosed
US-20070066840-A1 Grignard processes with increased content of diphenylchlorosilanes DOW CORNING CORPORATION 2007-03-22 US disclosed
US-20070010683-A1 Carbon-carbon bond creation method comprising the coupling of a transferable group and an acceptor group RHODIA-CHIMIE (FR) 2007-01-11 US disclosed
US-20060093933-A1 Polysilane-based charge transport materials S-PRINTING SOLUTION CO., LTD. (KR) 2006-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066826-A1 Grignard processes with improved yields of diphenylchlorosilanes as products AHR, GMNN, PAH CYP3A4 236/4885MAPK1 2760/4885CES1 3457/4885
US-20080139834-A1 Method of Making Phenyl-Containing Chlorosilanes with Aliphatic or Cycloparaffinic Hydrocarbon Solvents AHR, GRHPR, PAH CYP3A4 362/4885MAPK1 2254/4885CES1 2092/4885
US-20070010683-A1 Carbon-carbon bond creation method comprising the coupling of a transferable group and an acceptor group C9, NUDC, PIK3C2A CYP3A4 948/4885MAPK1 1303/4885CES1 3447/4885
US-20070066840-A1 Grignard processes with increased content of diphenylchlorosilanes GMNN, CCR8, GIGYF2 CYP3A4 498/4885MAPK1 1766/4885CES1 2920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.