Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 3/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23764113 | 0.78 | IL2 (0.39) | NUDT1JAK1JAK2JAK3 | |
| SCHEMBL23754207 | 0.75 | JAK1 (0.51) | EGLN2JAK1TYK2RAB9AJAK2 | |
| SCHEMBL2145114 | 0.71 | EGLN2 (0.49) | EGLN2JAK1TYK2JAK2JAK3 | |
| SCHEMBL13504386 | 0.71 | NUDT1 (0.62) | EGLN2NUDT1JAK1MKNK1JAK3 | |
| SCHEMBL19659253 | 0.67 | EGLN2 (0.50) | EGLN2NUDT1JAK1TYK2RAB9A | |
| SCHEMBL2144470 | 0.65 | JAK2 (0.56) | JAK1TYK2RAB9AJAK2MEN1 | |
| SCHEMBL13031263 | 0.64 | JAK1 (0.72) | JAK1TYK2JAK2JAK3 | |
| SCHEMBL3214328 | 0.64 | JAK2 (0.65) | JAK1JAK2JAK3 | |
| SCHEMBL3204109 | 0.62 | JAK2 (0.49) | EGLN2NUDT1JAK1TYK2JAK2 | |
| SCHEMBL23764043 | 0.62 | JAK1 (0.42) | JAK1JAK2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021161084-A1 | N-(4-FLUOROPHENYL)-5-PHENYL-[1,2,4] TRIAZOLO [1,5-A] PYRIDINE-2-CARBOXAMIDE DERIVATIVES AND THEIR SYNTHESIS THEREOF | NINGEGOWDA RAGHU (IN) | 2021-08-19 | — | — | WO | disclosed |