SCHEMBL23764237

SCHEMBL23764237

CC1(C)C=CC=C(N(c2ccccc2)c2cccc(-c3ccccn3)c2)C=C1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 5/20 0.34
BACE1 P56817 1/20 0.34
HRH3 Q9Y5N1 1/20 0.33
CETP P11597 1/20 0.33
DCTPP1 Q9H773 1/20 0.33
HTR1A P08908 1/20 0.32
HTR7 P34969 1/20 0.32
FFAR1 O14842 1/20 0.32
ABL1 P00519 1/20 0.32
BCR P11274 1/20 0.32
KAT6A Q92794 1/20 0.32
TLR4 O00206 1/20 0.32
TLR2 O60603 1/20 0.32
KDM4E B2RXH2 1/20 0.32
KDM6B O15054 1/20 0.32
KDM4A O75164 1/20 0.32
KDM5C P41229 1/20 0.32
KDM4C Q9H3R0 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
KDM3A Q9Y4C1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23764233 0.90 CYP1A2 (0.37) ABL1BCRKDM4EKDM6BKDM4A
SCHEMBL23764221 0.84 NOTUM (0.36) BACE1CETP
SCHEMBL23764225 0.84 NPC1 (0.36) KDM4ENPC1RAB9A
SCHEMBL23764224 0.82 KMO (0.39) BACE1CETPCYP2A6MAPTL3MBTL1
SCHEMBL23764418 0.77 ALDH1A1 (0.37) NPC1RAB9A
SCHEMBL5115970 0.77 CYP2A6 (0.46) TGFBR1HRH3CETPDCTPP1HTR1A
SCHEMBL30109153 0.77 CYP2A6 (0.46) TGFBR1HRH3CETPDCTPP1HTR1A
SCHEMBL16484524 0.77 CYP2A6 (0.46) TGFBR1HRH3CETPDCTPP1HTR1A
SCHEMBL23764229 0.76 MAPT (0.38) KDM4EMAPT
SCHEMBL5102763 0.76 CYP2A6 (0.44) TGFBR1BACE1HRH3CETPDCTPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 EP disclosed