SCHEMBL23764221

SCHEMBL23764221

CC1(C)C=CC=C(N(c2ccccc2)c2cccc(-c3ccncc3)c2)C=C1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.36
PRMT6 Q96LA8 1/20 0.35
PRKCI P41743 1/20 0.34
KIF11 P52732 1/20 0.34
ABHD6 Q9BV23 1/20 0.33
MKNK1 Q9BUB5 1/20 0.33
PIK3CA P42336 1/20 0.33
IMPDH2 P12268 1/20 0.32
BACE1 P56817 1/20 0.32
CETP P11597 1/20 0.31
NTRK1 P04629 1/20 0.31
CYP17A1 P05093 1/20 0.31
MAPK11 Q15759 2/20 0.31
MAPK14 Q16539 2/20 0.31
MAPK13 O15264 1/20 0.31
GCGR P47871 1/20 0.31
MAPK12 P53778 1/20 0.31
CSNK1D P48730 1/20 0.30
CHEK1 O14757 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23764229 0.90 MAPT (0.38) NOTUMPIK3CA
SCHEMBL23764224 0.88 KMO (0.39) PRMT6MKNK1BACE1CETPCYP17A1
SCHEMBL23764237 0.84 TGFBR1 (0.34) BACE1CETP
SCHEMBL23764223 0.81 KIF11 (0.37) KIF11MKNK1CYP17A1
SCHEMBL23764414 0.79
SCHEMBL23764225 0.79 NPC1 (0.36)
SCHEMBL23764239 0.77 GABRG2 (0.34)
SCHEMBL23764419 0.77 KCNA5 (0.33)
SCHEMBL20629310 0.76 HTT (0.30)
SCHEMBL16484601 0.76 NOTUM (0.58) NOTUMPRMT6PRKCIKIF11ABHD6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 EP disclosed