SCHEMBL23764417

SCHEMBL23764417

CC1(C)C=CC=C(N(c2ccccn2)c2cccc3ncccc23)C=C1

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.32
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
HIF1A Q16665 1/20 0.31
OPRM1 P35372 1/20 0.31
OPRL1 P41146 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23764413 0.82 KCNA3 (0.32) LMNAOPRM1OPRL1
SCHEMBL23764409 0.76 CYP2D6 (0.31) HIF1A
SCHEMBL18900785 0.74 SIGMAR1 (0.38)
SCHEMBL16484717 0.73 KDM4E (0.40) HRH3MEN1LMNAMAPTKMT2A
SCHEMBL23764207 0.72
SCHEMBL23764411 0.71 KDM4E (0.36) LMNAMAPT
SCHEMBL23764230 0.71 ACVR1 (0.37)
SCHEMBL23764415 0.70 LMNA (0.38) MEN1LMNAHSP90AA1MAPTHTT
SCHEMBL23764519 0.69 KDM4E (0.34) HRH3MEN1LMNAMAPTHTT
SCHEMBL23764524 0.68 KDM4E (0.33) LMNAMAPTHTTKMT2AHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 EP disclosed