SCHEMBL23764415

SCHEMBL23764415

CC1(C)C=CC=C(N(c2ccccc2)c2cccc3cccnc23)C=C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
HIF1A Q16665 2/20 0.34
EPAS1 Q99814 1/20 0.34
MAPT P10636 4/20 0.32
METAP2 P50579 2/20 0.32
METAP1 P53582 2/20 0.32
HDAC6 Q9UBN7 1/20 0.32
ALDH1A1 P00352 3/20 0.31
MMP2 P08253 2/20 0.31
TSHR P16473 2/20 0.31
KDM4E B2RXH2 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
CCR1 P32246 2/20 0.31
CCR5 P51681 2/20 0.31
CCR8 P51685 2/20 0.31
HPGD P15428 2/20 0.31
HSP90AA1 P07900 2/20 0.31
GMNN O75496 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23764411 0.80 KDM4E (0.36) LMNAMAPTALDH1A1KDM4ECCR5
SCHEMBL23764412 0.80 TNF (0.36)
SCHEMBL23764410 0.80 KCNA3 (0.34) LMNAHIF1AMAPTALDH1A1KDM4E
SCHEMBL23764418 0.78 ALDH1A1 (0.37) ALDH1A1CYP3A4CYP2D6HTTRAB9A
SCHEMBL19443891 0.78 ALDH1A1 (0.31) L3MBTL1MAPTALDH1A1KDM4ETDP1
SCHEMBL16484723 0.76 LMNA (0.48) LMNAL3MBTL1HIF1AMAPTMETAP2
SCHEMBL23764233 0.74 CYP1A2 (0.37) LMNAL3MBTL1HIF1AMAPTMETAP1
SCHEMBL23764419 0.74 KCNA5 (0.33) HDAC6
SCHEMBL23764237 0.74 TGFBR1 (0.34) LMNAL3MBTL1MAPTKDM4ERAB9A
SCHEMBL23764232 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 EP disclosed