SCHEMBL23764411

SCHEMBL23764411

CC1(C)C=CC=C(N(c2cccnc2)c2cccc3ccccc23)C=C1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
CCR5 P51681 1/20 0.33
SIGMAR1 Q99720 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23764412 0.87 TNF (0.36)
SCHEMBL23764410 0.87 KCNA3 (0.34) KDM4EALDH1A1LMNAMAPT
SCHEMBL18900785 0.84 SIGMAR1 (0.38) ALDH1A1SIGMAR1
SCHEMBL20629309 0.81 SIGMAR1 (0.32) SIGMAR1
SCHEMBL23764415 0.80 LMNA (0.38) KDM4EALDH1A1LMNAMAPTCCR5
SCHEMBL23764413 0.78 KCNA3 (0.32) KDM4ELMNA
SCHEMBL23764213 0.77 CYP11B1 (0.31)
SCHEMBL20404377 0.77 SIGMAR1 (0.31) SIGMAR1
SCHEMBL16484731 0.75 ALDH1A1 (0.46) KDM4EALDH1A1LMNAMAPTSIGMAR1
SCHEMBL23764224 0.74 KMO (0.39) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 EP disclosed