Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 2/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24079231 | 0.88 | GNAO1 (0.36) | GNAO1 | |
| SCHEMBL23919055 | 0.82 | CACNA2D1 (0.40) | GNAO1GNAI3GNAI1 | |
| SCHEMBL18745415 | 0.79 | CHRM5 (0.32) | — | |
| SCHEMBL23950964 | 0.79 | GNAO1 (0.32) | GNAO1 | |
| SCHEMBL22648508 | 0.77 | GNAO1 (0.37) | GNAO1 | |
| SCHEMBL30670277 | 0.77 | GBA1 (0.35) | GNAO1GNAI3GNAI1 | |
| SCHEMBL25133512 | 0.76 | CHRM5 (0.42) | GNAO1GNAI3GNAI1 | |
| SCHEMBL25133303 | 0.76 | SLC6A1 (0.34) | GNAO1 | |
| SCHEMBL25133300 | 0.76 | SLC6A1 (0.34) | GNAO1 | |
| SCHEMBL25133298 | 0.76 | SLC6A1 (0.34) | GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210253626-A1 | PRODRUGS OF FULVESTRANT | KI PHARMACEUTICALS, LLC | 2021-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253626-A1 | PRODRUGS OF FULVESTRANT | CYP19A1, PGR, CYP21A2 | GNAO1 2387/4885GNAI3 1178/4885GNAI1 1369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.