Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22648508 | 0.90 | GNAO1 (0.37) | GNAO1SIGMAR1ALDH1A1HTT | |
| SCHEMBL23765778 | 0.88 | GNAO1 (0.36) | GNAO1 | |
| SCHEMBL18745415 | 0.84 | CHRM5 (0.32) | ALDH1A1 | |
| SCHEMBL21472825 | 0.83 | ACHE (0.39) | GNAO1SIGMAR1ALDH1A1HTT | |
| SCHEMBL18595930 | 0.80 | CYP1A2 (0.34) | ALDH1A1 | |
| SCHEMBL15706251 | 0.80 | THRA (0.34) | GNAO1 | |
| SCHEMBL1104721 | 0.80 | SIGMAR1 (0.44) | SIGMAR1ALDH1A1HTT | |
| SCHEMBL25133415 | 0.79 | GNAO1 (0.39) | GNAO1SIGMAR1 | |
| SCHEMBL20259728 | 0.78 | CPN1 (0.30) | GNAO1 | |
| Bromide SCHEMBL4936619 | 0.78 | SIGMAR1 (0.43) | SIGMAR1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11191769-B2 | Fused thiophene compounds | BIOTHERYX, INC. (US) | 2021-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11191769-B2 | Fused thiophene compounds | SSB, ICAM1, VCAM1 | GNAO1 3753/4885SIGMAR1 3758/4885ALDH1A1 3761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.