Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980124 | 0.94 | APLNR (0.41) | APLNRPIK3CGESR1CYP19A1ESR2 | |
| SCHEMBL9740781 | 0.78 | ESR1 (0.41) | APLNRPIK3CGESR1CYP19A1ESR2 | |
| SCHEMBL11261059 | 0.77 | POLB (0.56) | MTNR1AMTNR1BPOLB | |
| SCHEMBL21157880 | 0.77 | CHRM2 (0.40) | APLNRMTNR1AMTNR1B | |
| SCHEMBL15757833 | 0.77 | ADRA1A (0.57) | CNR1MTNR1AMTNR1BCNR2 | |
| SCHEMBL10044940 | 0.75 | SLC6A4 (0.53) | PIK3CGMTNR1AMTNR1B | |
| SCHEMBL19776579 | 0.75 | APLNR (0.46) | APLNRPOLB | |
| SCHEMBL8161406 | 0.75 | APLNR (0.56) | APLNRCNR1MTNR1AMTNR1BCNR2 | |
| SCHEMBL22710291 | 0.74 | APLNR (0.38) | APLNRPIK3CGMTNR1AMTNR1BPOLB | |
| SCHEMBL19980286 | 0.74 | APLNR (0.38) | APLNRPIK3CGMTNR1AMTNR1BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925771-B1 | A PROCESS FOR THE PREPARATION OF SOLOMONAMIDE ANALOGUES | COUNCIL SCIENT IND RES (IN) | 2021-08-18 | — | — | EP | disclosed |