SCHEMBL2376831

SCHEMBL2376831

CC1(C)SCC(CO)S1.[NaH]

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TMEM97 Q5BJF2 3/20 0.37
SIGMAR1 Q99720 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2369369 0.98
SCHEMBL4865787 0.65
SCHEMBL10414835 0.62
SCHEMBL14000288 0.59
SCHEMBL1402798 0.59
SCHEMBL8313692 0.59 KMT2A (0.36) TMEM97SIGMAR1
SCHEMBL7668456 0.59
SCHEMBL13650783 0.55
SCHEMBL20680547 0.55
SCHEMBL11033412 0.53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011107867-A2 COMPOUND AND COMPOSITION AND THEIR USE IN THE TREATMENT OF DISEASES RELATED TO COPPER RETENTION KANDULA MAHESH (IN) 2011-09-09 WO claimed
US-20110218236-A1 COMPOUND AND COMPOSITION AND THEIR USES THEREOF KRISHANI BIOSCIENCES (P) LTD (IN) 2011-09-08 US claimed
WO-2011107867-A2 COMPOUND AND COMPOSITION AND THEIR USE IN THE TREATMENT OF DISEASES RELATED TO COPPER RETENTION KANDULA MAHESH (IN) 2011-09-09 WO disclosed
US-20110218238-A1 COMPOUNDS, COMPOSITIONS, FORMULATIONS AND THEIR USES THEREOF KRISHANI BIOSCIENCES (P) LTD (IN) 2011-09-08 US disclosed
US-20110218236-A1 COMPOUND AND COMPOSITION AND THEIR USES THEREOF KRISHANI BIOSCIENCES (P) LTD (IN) 2011-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110218236-A1 COMPOUND AND COMPOSITION AND THEIR USES THEREOF SLC26A4, SLC26A3, SLC10A1 TMEM97 1848/4885SIGMAR1 1726/4885
US-20110218238-A1 COMPOUNDS, COMPOSITIONS, FORMULATIONS AND THEIR USES THEREOF SLC10A1, ABCB11, NPC1L1 TMEM97 560/4885SIGMAR1 1089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.