Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM5A | P29375 | 2/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25606204 | 0.85 | LMNA (0.50) | L3MBTL1ALDH1A1LMNATSHRPABPC1 | |
| SCHEMBL4810374 | 0.85 | LMNA (0.50) | L3MBTL1ALDH1A1LMNATSHRPABPC1 | |
| SCHEMBL8458653 | 0.85 | LMNA (0.50) | L3MBTL1ALDH1A1LMNATSHRPABPC1 | |
| SCHEMBL18665116 | 0.84 | TSHR (0.52) | L3MBTL1ALDH1A1LMNATSHRKDM5A | |
| SCHEMBL8377126 | 0.84 | TSHR (0.52) | L3MBTL1ALDH1A1LMNATSHRKDM5A | |
| SCHEMBL9651504 | 0.84 | TSHR (0.52) | L3MBTL1ALDH1A1LMNATSHRPABPC1 | |
| SCHEMBL22920329 | 0.83 | DNM1 (0.46) | LMNATSHRMEN1KMT2A | |
| SCHEMBL18789608 | 0.81 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1LMNATSHRKDM5A | |
| SCHEMBL22920318 | 0.80 | ADH1C (0.39) | ALDH1A1LMNATSHRKDM5AMEN1 | |
| SCHEMBL20623310 | 0.78 | KDM5A (0.52) | L3MBTL1ALDH1A1LMNATSHRKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458590-B9 | POLYNUCLEOTIDES ENCODING -GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE | MODERNATX INC (US) | 2021-08-18 | — | — | EP | disclosed |